PREDICTED MALIGNANCY OF PULMONARY LESION BY USING TUMOR INSPECTOR VERSION 1 PROGRAM IN PHRAMONGKUTKLAO HOSPITAL

Authors

  • Jutamas Dechsanga Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine
  • Anan Wattanathum Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine
  • Virisorn Wongsrichanalai Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine
  • Kingpeth Promthong Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine
  • Banphatree Khomkham Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University
  • Rajalida Lapikorn Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University
  • Wannapon Suravorachet Department of Mathematics and Computer Science, Faculty of Science, Chulalongkorn University

DOI:

https://doi.org/10.55374/jseamed.v2i1.22

Keywords:

Endobronchial ultrasound, Malignancy, Pulmonary nodule

Abstract

Background:Bronchoscopy for diagnosis had been performed for decade for tissue diagnosis. Pulmonary nodule can be originated from any caused, ranging from benign granuloma and infectious process to malignancy. Establishing the etiology of pulmonary nodule in accurate manner assumes critical importance, since surgical resection in a patient with early-stage lung cancer provides the highest chance of cure. By the same token, avoiding thoracic surgery for benign SPN whenever possible does obviate significant morbidity. At present Endobronchial ultrasound have been performed more often. The characteristic of endobronchial ultrasound with guide sheath can be predicted which pulmonary nodule could be benign or malignant in picture. There will be vary in interpreted outcome due to depending on pulmonologist’s experienced. We developed a tumor inspector program V.1 for helping to interpreted characteristic of endobronchial ultrasound picture which make it more stable, faster to interpreted and used for further treatment planning. Objective: To evaluate accuracy in interpretation characteristic endobronchial ultrasound picture of tumor inspector program V.1 compared with three pulmonology interventionists agreement. Methods:Cross-sectional study including patients who had pulmonary nodule that undergo EBUS-GS and obtained pathological tissue diagnosis. Results:Two hundred and eight patients were included in this study, mean age 61 years old were studied. One hundred and twenty-six (60.58%) were male. Thirty-four (16.35%) patients had history of smoking. Thirty-four patients (16.35%) had previous malignancy. In study we used pathological report as a gold standard. There were sensitivity 90.6% ,specificity 22.5% ,PPV 65.2%, NPV 60% and accuracy 64.42% in humans interpretation that compatible with pathological report. And there were sensitivity 90.0%%, specificity 81.2%, PPV 88.5% ,NPV 84.4% and accuracy 87.0% in version 1 tumor inspector program. Conclusions:In patients with pulmonary nodule, tumor inspector V.1 program had significantly higher specificity and accuracy to predict malignancy possibility than three pulmonology interventionists agreement.gram.

Metrics

Metrics Loading ...

References

de Gracia J, Bravo C, Miravitlles M, et al. Diagnostic value of bronchoalveolar lavage in peripheral lung cancer. Am Rev Respir Dis 1993; 147: 649-52 DOI: https://doi.org/10.1164/ajrccm/147.3.649

Hsiao CJ, Tang CC, Hui C, et al. The value of transbronchial lung biopsy in the diagnosis of peripheral lung tumorsaccording to cell type. Chang Gung Med J 2000; 23: 584-89

Tang CC, Hsiao CJ, Chen H, et al. Value of bronchoalveolarlavage combined with transbtonchial lung biopsy in the diagnosis of peripheral lung cancer. Chang Gung Med J 2000; 23: 695-700

Wongsarakiat P, Wongbunnate S, Dejsomritrutai W, et al. Diagnostic value of bronchoalveolar lavage and postbronchoscopic sputum cytology in peripheral lung cancer. Respirology 1998; 3: 131-7 DOI: https://doi.org/10.1111/j.1440-1843.1998.tb00111.x

Schreiber G, McCrory DC. Performance characteristics of different modalities for diagnosis of suspected lung cancaer: summary of published evidence. Chest 2003; 123(suppl1): 115s-28s DOI: https://doi.org/10.1378/chest.123.1_suppl.115S

Baaklini WA, Reinoso MA, Gorin AB, et al Diagnostic yield of fiberoptic bronchoscopy in evaluating solitary pulmonary nodules. Chest 2000; 117: 1049-59 DOI: https://doi.org/10.1378/chest.117.4.1049

Chechati V. Bronchoscopic diagnosis of solitary pulmonary nodules and lung masses in the adsence of endobronchial abnormality. Chest 1996; 109: 620-25 DOI: https://doi.org/10.1378/chest.109.3.620

Gasparini S, Ferretti M, Secchi EB, et al. Integration of transbronchial and perectaneous approach in the diagnosis of peripheral pulmonary nodules or masses: experience with 1,027 consecutive cases. Chest 1995; 108: 131-137 DOI: https://doi.org/10.1378/chest.108.1.131

Radke JR, Conway WA, Eyler WR, et al. Diagnostic accuracy in peripheral lung lesions: factors predicting success with flexible fiberoptic bronchoscopy. Chest 1979; 76: 176-9 DOI: https://doi.org/10.1378/chest.76.2.176

Herth FJF, Ernst A, Becker HD, et al. Endobronchial ultrasound-guided transbronchial lung biopsy in solitary pulmonary nodules and peripheral lesions. Eur Respir J 2002; 20: 972-4 DOI: https://doi.org/10.1183/09031936.02.00032001

Paone G, Nicastri E, Lucantoni, G, et al Endobronchial ultrasound-driven biopsy in the diagnosis of peripheral lung lesions. Chest 2005; 128: 3351-7 DOI: https://doi.org/10.1378/chest.128.5.3551

Kurimoto N, Murayama, M, Yoshioka S, Nishisaka T, et al. Analysis of the interal structure of peripheral pulmonary lesions using endobronchial ultrasonography. Chest 2002; 122: 1887-194 DOI: https://doi.org/10.1378/chest.122.6.1887

Kau CH, Lin SH, Chen HC, et al. Diagnosis of peripheral lung cancer with three echoic features via endobronchial ultrasound. Chest, 2007; 132: 922-9 DOI: https://doi.org/10.1378/chest.06-3106

Downloads

Published

2018-06-27

How to Cite

1.
Dechsanga J, Wattanathum A, Wongsrichanalai V, Promthong K, Khomkham B, Lapikorn R, et al. PREDICTED MALIGNANCY OF PULMONARY LESION BY USING TUMOR INSPECTOR VERSION 1 PROGRAM IN PHRAMONGKUTKLAO HOSPITAL. J Southeast Asian Med Res [Internet]. 2018 Jun. 27 [cited 2024 Feb. 21];2(1):37-44. Available from: https://jseamed.org/index.php/jseamed/article/view/22

Issue

Section

Original Articles

Similar Articles

You may also start an advanced similarity search for this article.