A STUDY OF THE GLYCEMIC INDEX OF THE MEDICAL FOOD NEO-MUNE

Authors

  • Supawan Buranapin Department of Internal Medicine, Faculty of Medicine, Chiang Mai University

DOI:

https://doi.org/10.55374/jseamed.v2i2.11

Keywords:

Glycemic index, Neo-mune, glycemic control, TRIAL REGISTRATION Thai Clinic Trials Trgistry TCTR Identifier, TCTR20170906002

Abstract

Objective: To study the glycemic index of a medical food Neo-Mune. Material and Methods: Ten healthy volunteers with normal pancreatic function were enrolled in this study. All eligible subjects were asked to return to the research center a week later to consume 50 grams of glucose solution and their plasma glucose levels were measured at 0 (baseline), 30, 60, 90 and 120 minutes after the glucose consumption. A week after that, the same cohort consumed 94.97 g Neo-Mune (advised carbohydrate provision of 50 grams) and again, their plasma glucose levels were recorded at 0, 30, 60, 90 and 120 minutes after consumption. The glycemic index (GI) was calculated from the area under the glucose response curve of Neo-Mune divided by the area under the glucose response curve of the glucose solution, multiplied by 100. Results: The plasma glucose levels reached their highest levels at 30 minutes post-consumption and decreased gradually in both cases. However, the plasma glucose levels were lower at 30 and 60 minutes post Neo-Mune consumption compared to those after the glucose solution consumption. The GI of Neo-Mune was identified as 42.12, which classifies it as a low-GI food. Conclusion:Neo-Mune, a low-GI food, is expected to show a low postprandial glycemic excursion after consumption.

Metrics

Metrics Loading ...

References

Anderson JW, Baird P, Davis RH, Jr., et al. (2009) Health benefits of dietary fiber. Nutrition Reviews67: 188-205. DOI: https://doi.org/10.1111/j.1753-4887.2009.00189.x

Barclay AW, Petocz P, McMillan-Price J, et al. (2008) Glycemic index, glycemic load, and chronic disease risk--a meta-analysis of observational studies. The American Journal of Clinical Nutrition 87: 627-637. DOI: https://doi.org/10.1093/ajcn/87.3.627

Bouche C, Rizkalla SW, Luo J, et al. (2002) Five-week, low-glycemic index diet decreases total fat mass and improves plasma lipid profile in moderately overweight nondiabetic men. Diabetes Care 25: 822-828. DOI: https://doi.org/10.2337/diacare.25.5.822

Brand JC, Colagiuri S, Crossman S, et al. (1991) Low-glycemic index foods improve long-term glycemic control in NIDDM. Diabetes Care 14: 95-101. DOI: https://doi.org/10.2337/diacare.14.2.95

Canfora EE and Blaak EE. (2015) The role of polydextrose in body weight control and glucose regulation. Current Opinion in Clinical Nutrition and Metabolic Care18: 395-400. DOI: https://doi.org/10.1097/MCO.0000000000000184

do Carmo MM, Walker JC, Novello D, et al. (2016) Polydextrose: Physiological Function, and Effects on Health. Nutrients 8. DOI: https://doi.org/10.3390/nu8090553

Foster-Powell K and Miller JB. (1995) International tables of glycemic index. The American Journal of Clinical Nutrition 62: 871s-890s. DOI: https://doi.org/10.1093/ajcn/62.4.871S

Jarvi AE, Karlstrom BE, Granfeldt YE, et al. (1999) Improved glycemic control and lipid profile and normalized fibrinolytic activity on a low-glycemic index diet in type 2 diabetic patients. Diabetes Care 22: 10-18. DOI: https://doi.org/10.2337/diacare.22.1.10

Jie Z, Bang-Yao L, Ming-Jie X, et al. (2000) Studies on the effects of polydextrose intake on physiologic functions in Chinese people. The American Journal of Clinical Nutrition 72: 1503-1509. DOI: https://doi.org/10.1093/ajcn/72.6.1503

Ludwig DS. (2002) The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease. Jama 287: 2414-2423. DOI: https://doi.org/10.1001/jama.287.18.2414

Luscombe ND, Noakes M and Clifton PM. (1999) Diets high and low in glycemic index versus high monounsaturated fat diets: effects on glucose and lipid metabolism in NIDDM. The European Journal of Clinical Nutrition 53: 473-478. DOI: https://doi.org/10.1038/sj.ejcn.1600779

Mann J. (2001) Dietary fibre and diabetes revisited. The European Journal of Clinical Nutrition 55: 919-921. DOI: https://doi.org/10.1038/sj.ejcn.1601258

Miller JC. (1994) Importance of glycemic index in diabetes. The American Journal of Clinical Nutrition 59: 747s-752s. DOI: https://doi.org/10.1093/ajcn/59.3.747S

Salmeron J, Ascherio A, Rimm EB, et al. (1997a) Dietary fiber, glycemic load, and risk of NIDDM in men. Diabetes Care 20: 545-550. DOI: https://doi.org/10.2337/diacare.20.4.545

Salmeron J, Manson JE, Stampfer MJ, et al. (1997b) Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. Jama 277: 472-477. DOI: https://doi.org/10.1001/jama.277.6.472

Surojanametakul V. (2006) Glycemic index: food and health. Jounal of food 36: 183-187.

Tiihonen KK, Röytiö H, Putaala H, et al. (2011) Polydextrose functional fibre. Nutrafoods 10: 23-28. DOI: https://doi.org/10.1007/BF03223385

Van Schaftingen E, Detheux M and Veiga da Cunha M. (1994) Short-term control of glucokinase activity: role of a regulatory protein. The FASEB Journal 8: 414-419. DOI: https://doi.org/10.1096/fasebj.8.6.8168691

Venn BJ and Green TJ. (2007) Glycemic index and glycemic load: measurement issues and their effect on diet-disease relationships. The European Journal of Clinical Nutrition 61 Suppl 1: S122-131. DOI: https://doi.org/10.1038/sj.ejcn.1602942

Willett W, Manson J and Liu S. (2002) Glycemic index, glycemic load, and risk of type 2 diabetes. The American Journal of Clinical Nutrition 76: 274s-280s. DOI: https://doi.org/10.1093/ajcn/76.1.274S

Wolever TM and Jenkins DJ. (1986) The use of the glycemic index in predicting the blood glucose response to mixed meals. The American Journal of Clinical Nutrition 43: 167-172. DOI: https://doi.org/10.1093/ajcn/43.1.167

Wolever TM, Jenkins DJ, Jenkins AL, et al. (1991) The glycemic index: methodology and clinical implications. The American Journal of Clinical Nutrition 54: 846-854. DOI: https://doi.org/10.1093/ajcn/54.5.846

Yanai H, Katsuyama H, Hamasaki H, et al. (2014) Effects of Carbohydrate and Dietary Fiber Intake, Glycemic Index and Glycemic Load on HDL Metabolism in Asian Populations. Journal of Clinical Medicine Research6: 321-326. DOI: https://doi.org/10.14740/jocmr1884w

Downloads

Published

2018-12-26

How to Cite

1.
Buranapin S. A STUDY OF THE GLYCEMIC INDEX OF THE MEDICAL FOOD NEO-MUNE. J Southeast Asian Med Res [Internet]. 2018 Dec. 26 [cited 2024 Apr. 17];2(2):67-75. Available from: https://jseamed.org/index.php/jseamed/article/view/11

Issue

Section

Original Articles

Similar Articles

1 2 3 4 5 > >> 

You may also start an advanced similarity search for this article.